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Arbor Pharmaceuticals Inc.

September 26, 2007

Arbor Pharmaceuticals Launches ZINOTIC™ – A Novel Treatment Developed to Relieve the Pain of Outer Ear Infections While Eliminating Infection and Protecting the Skin

Raleigh, NC – Arbor Pharmaceuticals announced today that the company’s first product, ZINOTIC™, has recently been launched in the US and is now available to healthcare practitioners to prescribe for their patients suffering from common outer ear infections. ZINOTIC™ is a novel ear solution that combines chloroxylenol, pramoxine and zinc acetate and is indicated for the treatment of acute otitis externa, or AOE, which is also referred to as swimmer’s ear. ZINOTIC™ combines three unique medications in a patented ear solution. Each component of ZINOTIC™ is important to help decrease symptoms and advance the healing process. Because children are most often affected by outer ear infections having all three medicines in a single topical solution delivers a high level of convenience to the parents and patients.
 
According to Dr. Jeffrey DeWester, a practicing physician and Arbor’s Medical Director, “Ear infections are a very common problem and one of the biggest reasons that a child visits a doctor. Parents bring their child to the doctor because their infected ear is in great pain; touching the ear can bring the child to tears. ZINOTIC™ was developed to help rapidly relieve pain while simultaneously eradicating infection and helping to heal the damaged skin inside the ear. Together, these unique properties offer a real advantage for patients and parents.” Dr. DeWester further commented, “The recently published AOE clinical practice guideline supports the position of a product like ZINOTIC™ in therapy particularly with the incorporation of an effective pain reliever and a non-antibiotic agent that addresses the underlying infection.”
 
“The launch of ZINOTIC™ represents a very important milestone for Arbor as it demonstrates the company’s commitment to provide novel therapeutic options for pediatricians and their patients. More importantly, we believe that ZINOTIC™ will be an important treatment option for children suffering from AOE as ZINOTIC™ is the only treatment that effectively addresses the three goals of AOE therapy - pathogen eradication, pain relief and protecting the ear canal skin” states Jarrett
Disbrow, President & Chief Executive Officer of Arbor Pharmaceuticals, Inc. Arbor Pharmaceuticals has partnered with an established specialty pharmaceutical company to distribute and promote ZINOTIC™ to key pediatricians and otolaryngologists (ENTs) across the U.S. ZINOTIC™ is available by prescription only through retail pharmacies across the U.S. For more information about ZINOTIC™, please visit www.zinotic.com.
 
The most common side effects of pramoxine (contained in ZINOTIC™) include redness, irritation, swelling, burning, stinging, pain or dryness at the affected area. Treatment with ZINOTIC™ should not be continued for longer than ten days and the source of infection and/or inflammation or sensitization evaluated to determine whether therapy should be changed.
 
About Arbor Pharmaceuticals
Arbor Pharmaceuticals is a Raleigh, North Carolina based specialty pharmaceutical company focused on the licensing, development, and commercialization of novel products for pediatricians. Founded in April 2006, Arbor actively seeks out unique, patent-protected therapies proven to effectively treat the most common pediatric illnesses. ZINOTIC™ is the first commercialized product from Arbor Pharmaceuticals, and the company is currently licensing and developing additional products for significant pediatric conditions. Arbor Pharmaceuticals collaborates with pharmaceutical development companies and established promotional partners in the pharmaceutical industry to develop and market their products in order to serve the needs of pediatricians throughout the US.
 
To learn more about Arbor Pharmaceuticals, visit www.arborpharma.com or send email inquiries to info@arborpharma.com.